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Jo's Story


Child B is currently under investigation for significant gastrointestinal symptoms, including chronic constipation, defecatory incontinence, and associated multisystem features. I am concerned that there may have been an attempt to label her condition as “functional” despite clear and documented evidence of structural, neurological, and genetic contributors to her symptoms.

Summary of Key Findings:
- Confirmed slow transit constipation on colonic transit study (16/12/2024) with marked faecal loading.
- Defecatory incontinence significantly impacting quality of life and hygiene.
- Moderate thoracolumbar scoliosis, as documented radiologically.
- Hypermobile Ehlers-Danlos Syndrome (hEDS) — a multisystemic connective tissue disorder well known to cause dysautonomia and gastrointestinal dysmotility.
- Diagnosed Autism Spectrum Disorder (ASD) and ADHD — both of which are independently associated with altered gut motility, sensory sensitivity, and atypical pain perception.
- History of lipoblastoma removal in infancy, raising concerns about potential surgical or neural impact.
- Chest discomfort requiring investigation to rule out residual effects from prior abdominal pathology.
- Recommendations from Professor Mike Thomson (10 May 2024) for:
- Rectal biopsy to exclude Hirschsprung’s disease (ultrashort segment)
- Lumbosacral MRI scan
- Upper GI endoscopy and Bravo pH study
- Extensive blood workup, including coeliac screen, zinc, vitamin D, folate, ESR, CRP, thyroid, and faecal calprotectin/elastase

These findings and referrals strongly indicate a complex, organic cause of symptoms involving gastrointestinal motility, connective tissue fragility, neurological regulation, and potential immune/allergic drivers.

Functional Labelling is Inappropriate:
The Rome IV criteria for functional bowel disorders specifically state that such diagnoses should only be made in the absence of identifiable structural, inflammatory, metabolic, or neurological causes. In Child B's case, multiple red flags are already present, including:
- Confirmed structural abnormality (scoliosis)
- Neurodevelopmental disorders affecting gut-brain axis
- Genetic connective tissue disorder (EDS)
- Suspicion of Hirschsprung’s disease
- Confirmed slow-transit pattern on imaging
- Severe incontinence and need for escalating laxative regimes

To attribute this complex clinical picture to a functional disorder risks mismanagement, stigma, delayed intervention, and emotional harm to the child and family. This also has implications for educational support, EHCP funding, and access to specialist care.

Request:
I respectfully request that any reference to “functional gastrointestinal disorder” be reviewed and removed from her records unless and until all organic causes have been fully investigated and definitively excluded. Further, I request that:

1. Diagnostic follow-through is completed in full (including MRI, rectal biopsy, as recommended).
2. Her bowel and continence needs are recognised as part of a neurogenetic and structural disability profile.
3. This medical complexity is accurately reflected in all clinical summaries, EHCP documents, and multidisciplinary planning.

I trust that Child B's case will be approached with the diagnostic rigor and multidisciplinary support it requires I have requested Martha’s rule since 24 June and kings have consistently refused me they have also demanded Child B be awake during nasal peg being inserted which she was unable to do and I find a breach of reasonable adjustments given you can have under anaesthesia


On Fri, 25 Jul 2025 at 08:51, Jo  wrote:

FYI
---------- Forwarded message ---------
From: Jo
Date: Fri, 25 Jul 2025 at 08:46
Subject: Re: Ref: 6373 & 6374
To: COMPLAINTS (KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST) <kch-tr.complaints@nhs.net>

Despite repeated emails to PALS and Dr. Rupasinghe, Child B was only seen on the ward after I physically attended and demanded she be reviewed on 18 July, following an A&E admission on 16 July. Since then, there has been no meaningful update, no structured clinical review, and no escalation to appropriate specialists, despite documented bradycardia, ongoing fatigue, nutritional decline, chronic gastrointestinal symptoms, and clear immune dysregulation concerns.

To date, only basic electrolytes were checked on the ward, and I have not been given the results of those tests, which I understand were drawn on or around 24 July. Prior to that, the broader blood panel arranged by Colchester was only completed after I demanded it—and even then, it failed to include key tests linked to Child B’s family history and known clinical risks, such as, immunoglobulins,  antibodies, or cytokine profiles and despite known very low esr 2 years ago as per sibling!

The only relevant tests included from our family’s known clinical profile by Colchester were homocysteine and cortisol, but both were taken at approximately 1:00 PM, which significantly compromises their clinical value:

• Cortisol: As per standard NHS and endocrine guidelines, morning cortisol must be drawn between 8:00–9:00 AM. A 1:00 PM sample does not meet diagnostic standards and cannot reliably be used to assess adrenal function.
• Homocysteine: National guidance advises fasting morning collection. Afternoon draws may result in false reassurance, particularly in patients with suspected methylation or B-vitamin pathway issues—as is the case across multiple family members.

Moreover, I have submitted evidence that Child B may have IL-6 receptor autoantibodies, like her sibling Child A. This means her CRP may be falsely low even in the presence of inflammation, creating a dangerous blind spot if used in isolation to guide clinical decisions. Despite this, there has been no immunology input, no cytokine or autoantibody testing, no nutritional reassessment, and no safeguarding oversight, even as Child B's weight has dropped to the 0.4th centile and her documented bradycardia (HR as low as 41 bpm) has not prompted cardiology review.

Jo


On Fri, 11 Jul 2025 at 11:39, COMPLAINTS (KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST) <kch-tr.complaints@nhs.net> wrote:
Dear Jo,

Thank you for your complaint which has been logged under case ref XXXX & XXXX.  I am sorry that you have had cause to contact us and regret that it has been necessary to bring these matters to our attention.

I am writing to confirm that your complaint has been logged and Lisa Mercer,  the Complaint Officer assigned has been included in this email to help aid any future contact.

It would also be helpful to understand if you need any adjustments to help with making the service accessible to you. If you need communication support such as an interpreter or information in another language, audio, Braille, Easy Read or large print, please let us know.

Please note we will be sending your response in writing via email, unless you inform us otherwise.

If you have any further questions or queries then please do not hesitate to contact us.

Kind Regards

Patient Complaints Team
0203 299 4618 - Option 8
Email: kch-tr.complaints@nhs.net

At King’s, we are a KIND, RESPECTFUL TEAM
                                         


From: Jo   
Sent: 06 July 2025 10:02
To: COMPLAINTS (KING'S COLLEGE HOSPITAL NHS FOUNDATION TRUST) <kch-tr.complaints@nhs.net>; enquiries@cqc.org.uk
Subject: Urgent Clinical governance kings & CQC



This message originated from outside of NHSmail. Please do not click links or open attachments unless you recognise the sender and know the content is safe.
Governance Team
King’s College Hospital NHS Foundation Trust
Denmark Hill
London SE5 9RS

Subject: Formal Complaint – Diagnostic Failures, Immunology Oversight, and Discharge Against Clinical Evidence in the Care of Child A and  Child B.

Dear Sir/Madam,

I am raising a formal complaint regarding serious and ongoing failures in the clinical care of my daughters — Child A and Child B — whose cases were partially managed under services at King’s College Hospital.

These failings include:
- Incomplete investigation and unsafe discharge (Child A),
- Failure to re-evaluate longstanding abnormal immunology (Child B), and hirchsprung test Child B
- Endorsement of coercive care conditions at a local level (Colchester), and
- A pattern of diagnostic bias which compromised both safeguarding and clinical standards.
1. Child A – Discharged from Immunology and Gastroenterology Despite Active Investigation
Child A was discharged from both immunology and gastroenterology at King’s while investigations were incomplete, and I had advised she was having abnormal results flag up these include -
- Anti-IL6RA autoantibodies confirmed by Dr. Rainer Doffinger (Addenbrooke’s, 2025),
- Abnormal TH17 cytokine profile: reduced IFNγ, IL-17, and IL-2,
- Persistently raised IgE >4000 kU/L,
- Positive ANA (1.5) and dsDNA (20 IU/mL), rechecked as dsDNA (30 IU - kings)
- Ongoing fatigue, hypopigmented patches, and immune-related symptoms. School attendance less than one day per week

Dr. Doffinger explicitly recommended follow-up testing and genetic screening via the R15 PID panel, yet these results have not been disclosed in Colchester clinic letter , and Child A was discharged without escalation.
2. Child B – Ignored Immunology Red Flags
Child B's records, including documents from Nottingham Children’s Hospital (2016–2017), showed:
- A low white cell count,
- Borderline low mannose-binding lectin (MBL),
- A bronchoalveolar lavage showing macrophages and lymphocytes,
- A family history of bronchial issues pneumonia repeated chest infections- mild dilated bronchials, immune dysfunction, and connective tissue disorders.

Despite being made aware of this history, King’s failed to initiate any immune follow-up or referral, even as Child A developed parallel abnormalities.
3. Diagnostic Overshadowing and Historical Bias
I am deeply concerned that historical psychosocial narratives, contributed to inappropriate minimisation of genuine clinical risk — including:
- Misattribution of physical symptoms,
- Failure to pursue genetic or immunological investigation,
- Assumptions that symptoms were psychosomatic in origin — despite abnormal labs and specialist alerts.
4. Inappropriate Conditions on Care – Dr Andrea Turner (Colchester)
Dr. Andrea Turner (Colchester General Hospital) made access to psychological care for Child B conditional upon her attending a joint appointment with both paediatrics and psychology. This was communicated through her PA in writing, who stated that if Child B found a joint appointment too overwhelming, then “psychology input will not be possible via Acute Paediatrics at Colchester Hospital.”

This effectively amounts to a withdrawal of psychology support based on Child B's neurodivergent needs and trauma history. It:
- Fails to offer reasonable adjustments,
- Places pressure on a child to comply with inflexible structures in order to access basic services,
- Undermines clinical safeguarding, particularly in complex neurodevelopmental or trauma-affected children.
5. Enabling of Local Mismanagement – Dr Rupasinghe (King’s)
Dr. Rupasinghe, involved in Kristina’s care at King’s, was aware of the immunology issues and Addenbrooke’s input. He failed to act on:
- The need for further genetic screening and antibody confirmation,
- The inappropriate minimisation of Child A’s immune profile by Colchester,
- Dr. Turner’s threats to withdraw care without compliance regarding Child B
Allowing Colchester to control MDT meetings without family input - nhs no decision about me without me and despite there had been known errors made by Colchester

By deferring Child A’s care back to a known failing system, Dr. Rupasinghe and King’s as a whole became complicit in the ongoing mismanagement and diagnostic neglect.
6. Child A Now Has No Paediatric Oversight or – Immunology Appointment at Addenbrooke’s Cancelled Without Explanation
Since Child A was discharged from King’s, her care has been left fragmented and unsupported. Most seriously:
- Her immunology follow-up appointment at Addenbrooke’s was cancelled without clear explanation evidenced in sar as being cancelled by clinic where her local paediatrician works pt
- She now has no designated paediatric clinician in Colchester as per there last clinic letter ,
- And there is no clear coordinated plan for re-investigation or specialist oversight, despite abnormal TH17 cytokine results, autoantibodies, and Addenbrooke’s direct recommendation.

This represents a safeguarding failure. Without any lead clinician — and with Colchester having shown repeated clinical bias — Child A is now clinically stranded.

Formal Requests
In light of these serious concerns, I request:

1. A full internal review into Child A’s discharge from both immunology and gastroenterology at King’s.
2. Immediate re-referral for Child A to:
 - Clinical Immunology (including R15 panel and IL6RA retesting), or referral to GOSH immunology given concerns
 - Gastroenterology Dr Rupasinge to confirm and clarify he is still happy to discharge Child A from gastroenterology in light of all results
3. A full immunology referral and assessment for Child B, including review of MBL, white cell trends, and family-linked risk. Due to Child B's needle phobia we ask all bloods are done along with the hirschprung biopsy when she will be under anaesthetic
4. A safeguarding and governance review into:
 - Why these concerns were dismissed across both children’s care,
 - How coercive conditions (e.g. Dr Turner’s demands) were allowed to persist,
 - What changes will be made to ensure families with complex conditions are managed with clinical neutrality and accountability.
5. A written response outlining next steps and what King’s will do to prevent further harm.
6. That King’s College Hospital assume direct responsibility for Child A's paediatric oversight by formally designating Dr. Wacks — who has already seen her sister, Child B — as Child A's named paediatric consultant and do the same for Child B
7. That King’s urgently refer Child A to Great Ormond Street Hospital (GOSH) Immunology to ensure her care is led by a specialist centre with experience in immune dysregulation and rare paediatric phenotypes.
This case should have had Martha’s law applied and a senior review taken place especially given that Dr Rupasinge had chosen advise from Colchester over his own colleague Dr Wacks, Prof Thomson and Great Ormond St Spinal Team
Please acknowledge this complaint and confirm your process for formal investigation. I am happy to provide further documentation if needed and am prepared to escalate this complaint to NHS England, the GMC, or the CQC if these concerns are not addressed transparently and in full.

Sincerely,


Jo  

Ignored Expert Recommendations – Professor Mike Thomson (May 2023)
Child B was reviewed by Professor Mike Thomson, a Consultant in Paediatric Gastroenterology, who made a series of urgent clinical recommendations following his review on 10 May 2023. These included:

- Concerns about possible spina bifida occulta, lipoblastoma scarring, and underlying Hirschsprung’s disease (suggesting referral for rectal biopsy and MRI),
- Recommendations for Bravo pH, upper GI endoscopy, chest CT, and full gastrointestinal, endocrine and immunology screening,
- Noted history of defecatory incontinence, abdominal pain, positional scoliosis, urticaria, and possible atopy, with overlapping features of Ehlers-Danlos Syndrome,
- A request for a complete workup including:
FBC, ESR, LFTs, U&E, calcium, phosphate, ferritin, coeliac screen, total IgA, IgE, zinc, B12, folate, vitamin D, TFTs, faecal calprotectin, elastase, and more.

Despite the above, many of these investigations were never carried out by Colchester, and King’s failed to intervene, even after this expert letter was shared.

This represents a further breach of continuity of care and places Child B at risk due to:
- Ongoing bowel and gastrointestinal dysfunction, weight now 0.4 percentile
- Overlapping atopic and autoimmune concerns (e.g. urticaria, abnormal stools, fatigue),
- EDS with neurodivergence (dyslexia, elective mutism, fatigue),
- Lack of timely exclusion of structural abnormalities (e.g. Hirschsprung’s, spinal causes).Additionally, due to Colchester’s misreporting of a spinal MRI, Georgia is now under the care of Great Ormond Street Hospital (GOSH) for spinal management. This highlights further systemic diagnostic failings and reinforces the need for national centre oversight in her case.



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